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When comparing the genomes of different lineages at the nucleotide sequence level a number of genomic differences were revealed.
As a single base-pair alteration may not affect annealing of sequences during microarray analysis, these subtle genomic differences were not identified.
All other genomic differences were limited to SNP or deletions/insertion of less than 3 bp (Fig. 4, Table 1 and Table S2).
Characteristic genomic differences were found between GCB and non-GCB DLBCL from the array data.
Other than the IS elements, notable large-scale genomic differences were also indicated.
The small replicons pReCFN42a and pRetMim1c were partially conserved and large genomic differences were found in the symbiotic plasmids.
Similar(52)
Because of the relatively short divergence times of domestic animals from their wild ancestors, genomic differences are likely to be subtle.
Somatic genomic differences are found in both normal cellular differentiation, as seen in the immune system, and in the progression of diseases such as cancer.
The interpopulation genomic differences are presented in the supplementary figure S1, Supplementary Material online.
In summary, sex, diet, species, physiology and genomic differences are all factors to consider when analyzing combined QTL datasets.
The size and structure of a study cohort are the main limiting factors in such studies, as the individual impact of genomic differences is usually small.
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