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Our findings demonstrate the important genomic differences of Asian ancestral group from the others, and highlight the need for further genomic studies focused on individuals outside of European ancestry to describe the full range of functionally important variations in humans.
The B. anthracis-specific chromosomal sequences found elucidate genomic differences of these three closely-related bacteria.
Interestingly, sub-telomeric instability was associated with the clinical phenotype, while Ty element insertion regions determined genomic differences of natural wine fermentation strains.
Recent analyses of mammalian genomes revealed that the expansion and contraction of gene families contribute much more than expected to the genomic differences of mammals [ 1].
In patients, the exact place in tumor progression/growth is always different and thus this alone can explain expression differences, as opposed to the inherent character of genomic differences of the tumor.
In order to eliminate the genomic differences of H37Ra and H37Rv in our analysis, SNVs and InDels shared between H37Ra and H37Rv were further filtered and annotated for gene locus and mutation types with the nearest coding sequences.
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In addition, the sheer number of differences between genomes makes it impossible to link genomic differences to any particular aspect of symbiosis.
As a consequence, differences between the rodent parasites especially at the genomic level have not been fully elucidated as yet and thus linking genomic differences to phenotypic traits of these parasites have been difficult.
Statistical analysis is used to define each variable region providing a robust and reliable method for rapid identification of genomic differences independent of annotated gene boundaries.
The popular belief used to be that SNPs represent the vast majority (about 0.1% of the total nucleotide content of the genome) of genomic differences in humans.
We have computed the total number of genomic differences between pairs of individuals whose DNA sequences are available from the "1000 Genomes" project.
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