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Somatic genomic differences are found in both normal cellular differentiation, as seen in the immune system, and in the progression of diseases such as cancer.
Because of the relatively short divergence times of domestic animals from their wild ancestors, genomic differences are likely to be subtle.
The interpopulation genomic differences are presented in the supplementary figure S1, Supplementary Material online.
In summary, sex, diet, species, physiology and genomic differences are all factors to consider when analyzing combined QTL datasets.
For recently diverged taxa connected by gene flow, such as the two subspecies of the willow warbler, genomic differences are expected to be few but informative about adaptive divergence [ 28, 29].
Given the close relatedness between EDM1c and EDM123C, as witnessed by both sequence similarity and gene content, there can be little doubt that these isolates are clonally related, and genomic differences are probably due to evolution taking place in the gut.
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When comparing the genomes of different lineages at the nucleotide sequence level a number of genomic differences were revealed.
As a single base-pair alteration may not affect annealing of sequences during microarray analysis, these subtle genomic differences were not identified.
All other genomic differences were limited to SNP or deletions/insertion of less than 3 bp (Fig. 4, Table 1 and Table S2).
Characteristic genomic differences were found between GCB and non-GCB DLBCL from the array data.
Other than the IS elements, notable large-scale genomic differences were also indicated.
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