Sentence examples for genomic determinants from inspiring English sources

Our needs include searching whole genomes for genomic determinants for phenotypic differences between isolates.

At present, 19 Shewanella strains from diverse environments have been sequenced providing a unique opportunity for comprehensive comparative analyses of their genomes and for revealing genomic determinants of the various phenotypes of the species.

Participants selected for this study were part of an integrative genomics study with a primary aim of identifying novel genomic determinants of CHD.

This study identifies TFBSs as differential genomic determinants of retroviral target site selection in the human genome, and suggests that transcription factors binding the LTR enhancer may synergize with the integrase in tethering retroviral pre-integration complexes to transcriptionally active regulatory regions.

Secondary objectives include response rate, progression-free survival, toxicity, quality of life, and exploratory evaluations of tumor tissue and blood samples for biologic or genomic determinants of outcome.

In this review, we discuss the potential genomic determinants of host anti-tumour immunity – mutational load, driver alterations, mutational processes and neoantigens – and their relationship with immunity in breast cancer.

Another genomic determinant, the duplication span, is identified as exerting a significant negative effect on sequence rate asymmetry among paralogs.

The active Cas10 could be particularly beneficial in thermal environments, in agreement with the previous observations that identified Cas10 as a prominent genomic determinant of the thermophilic life style [ 2, 54].

Much like in eukaryotic genes, the nucleosomal landscape of the HIV-1 promoter and its position within genomic chromatin are determinants of its transcriptional activity.

As a preliminary step towards understanding genomic and transcriptomic determinants of phenotypic differences between Plasmodium species, we have performed a comprehensive analysis of constraints on protein coding regions, upstream regions and gene expression between Plasmodium species.

Building the capacity for human biological sample collection into existing surveillance networks has the potential to facilitate a more comprehensive, population-based evaluation of genomic and environmental determinants of health outcomes.