Sentence examples for genomic consequence of from inspiring English sources

The drug response signatures reproduced the Connectivity Map concept initially developed by the Broad Institute 25 in which the genomic consequence of drug exposure is used to connect drug effect to disease signatures.

These aspects have been extensively developed and thoroughly documented by W. Shields in his book on the relationship between philopatry and inbreeding [ 2]: " One potential advantage of inbreeding, then, is that its genomic consequence of maintaining interlocus allele associations may permit more faithful transmission of coadapted genomes than would be possible with wider outbreeding".

This was done in order to investigate the genomic consequences of several rounds of genome duplication in the vertebrate lineage.

To gain more detailed insight into the genomic consequences of domestication, we compared the full genomes of 26 diverse wild accessions and 7 elite cultivated genotypes sequenced to an average depth of 30 70 × , and 29 breeder-preferred cultivated genotypes previously sequenced9.

Fuller PM, Eikermann M. Genomic consequences of sleep restriction: the devil is in the details.

We assayed the genomic consequences of disregulating the replication licensing mechanisms by RNAi depletion of geminin.

As representatives of distinct symbiotic lifestyles, these bacterial partners are useful models to examine the genomic consequences of diverse species associations.

We conclude that the genomic consequences of introgression caused the attraction of distant lineages in phylogenetic tree space, and that introgressive and divergent signals can be disentangled to produce a robust estimate of the phylogenetic history of the species.

To analyze the genomic consequences of Ets-1 over-expression in these ovarian cancer cells, we conducted a human gene microarray.

Therefore, it seems probable that the fitness increase generated by exposure to 100 mM EMS is the product of unexpected genomic consequences of high mutation rates coupled with the genomic effects of self-fertilization.

However, few analyses have explored the genetic and genomic consequences of allopolyploidy in natural systems.