Sentence examples for genomic complexity and from inspiring English sources

However, these previous studies have involved only a limited number of genes, with genome-wide approaches being precluded by both genomic complexity and cost [ 10].

These data are consistent with a previous observation that an increase of genomic complexity and physiological functionality is generally associated with a more complex regulation of gene expression since the additional genetic information has to be integrated into the existing regulatory networks that operate in a bacterial cell [ 17].

Insel, T. R. & Cuthbert, B. N. Endophenotypes: bridging genomic complexity and disorder heterogeneity.

The prevalence of each signature varied between patients both in absolute and relative contribution, confirming genomic complexity and heterogeneity of MM (Fig. 4c, d).

By leveraging over 2,100 samples from existing large scale studies, we are able to find an inherent cell heterogeneity in clinically characterized immune infiltrates, a strong link between estrogen receptor activity and infiltration in normal and tumor tissues, changes with genomic complexity, and identify characteristic differences in lymphocyte expression among molecular groupings.

We show the genomic complexity and heterogeneity of IBCs, which globally look like nIBCs.

However, the sequencing of numerous fungal species indicates an extreme diversity of genomic complexity, genome size, and genomic landscapes, ranging from those fungi with compact genomes to fungi where massive transposable element (TE) invasion took place, eventually resulting in genome sizes larger than that of A. thaliana (e.g., Spanu et al. 2010).

Although the above findings for loblolly pine are restricted by the limited availability of the data, this study is the first attempt to address the questions of exon-intron structure and genomic complexity in this species, and will likely stimulate further studies.

However, recent work questioning the correlation between Ne and genomic complexity urge caution (Whitney and Garland 2010, but see Lynch 2011).

NGS studies of the CLL genome [ 33, 34] have effectively elucidated the level of genomic complexity in CLL, and have revealed that the average number of non-silent mutations (that is, mutations that alter the protein sequence) is 10 to 20 per each sequenced CLL sample (out of approximately 1,000 somatic mutations per sample detected genome-wide).

To better understand the potential functional relevance of the sHsps in rice, it is important to understand their genomic complexity, expression profiling and tissue distribution.