Sentence examples for genomic circuit from inspiring English sources
The roles of E2F transcription factors and their interactions with RB related proteins in cell cycle regulation is well established and we have described a RB1/E2F3 genomic circuit specifically operating in the GU subtype of tumors [ 6].
We describe examples of genomic control circuits that underlie developmental transitions and cellular activation states within the immune system.
Albeit the availability of the high-throughput genomic data, the regulatory circuit in ESC still await quantitative and realistic models to be described.
The siRNA nanostructure technique allows optically addressable release of siRNA and provides an effective approach for precise perturbation of gene circuits without permanent genomic medications.
In particular, the previously proposed neuronal circuit modules, feedback signals, and genomic mechanisms are considered to make predictions in this manner.
Both approaches revealed a similarity between human Wnt5 paralogs expression patterns (see Additional file 1, Panel A and B), supporting the previously referred hypothesis of genomic conservation related to a responsive backup circuit [ 34], in which both genes participate.
Cancer is a complex disease in which both genomic and environmental factors affect the functioning of the molecular circuits leading to the so-called acquired capabilities of cancer [ 1].
The unraveling of this organism's genomic blueprint would help in understanding the evolutionary events that underpin the circuits of growth and virulence optimization in the genus Mycobacterium.
To assess APP copy number in single neurons, an optimized microfluidic protocol to assess genomic copy number via qPCR using a Biomark HD 48.48 Dynamic Array integrated fluidic circuit (IFC) (Fluidigm, South San Francisco) was adapted from gene expression protocols.
Moreover, impedimetric detection is found to be a promising technique for point-of-care genomic detection because the impedimetric signal can easily be analyzed by miniaturized electrical circuits.
