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Further analysis of the genome sequence of the adapted strain compared to the parent should reveal the genomic changes responsible for increased D-xylose fermentation.
Over the past decade, numerous groups have sought to identify the genomic changes responsible for these phenotypes.
Identifying the genomic changes responsible for the increased pathogenicity of this FWPV variant will require considerable effort in sequencing and molecular virology.
Contrasting the gene inventories of insects to those of the nematodes provides insight into the genomic changes responsible for their diversification.
These studies are the initial steps in a coordinated effort by the Daphnia Genomics Consortium [ 18] to build the necessary data banks and reagents needed to discover genomic changes responsible for the phenotypic diversity within the genus and to gain new insights into crustacean biology.
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At a certain length, the telomeres signal the cell to stop dividing, since too short telomeres may cause genomic instability that accelerates the accumulation of genetic changes responsible for tumorigenesis.
A number of molecular mechanisms have been described that are responsible for genomic changes [ 1].
Widespread distributions of transposable DNAs, such as IS elements, have been implicated to be responsible for large genomic changes, and also provide a rich source of repetitive sequences to apply our method.
However, the use of aCGH in our current study limits the results to identification of large-scale genomic changes, such as gain or loss of genes, responsible for phenotypic changes.
In other words, phyla could provide prokaryotic genomes with a sense of 'inertia' (or memory) while environmental factors affecting base composition may be responsible for inducing more rapid genomic changes.
A comprehensive diagnostic tool for genetic syndromes using whole-genome DNA sequencing will enable the identification of all possible genetic and/or genomic changes in each individual and their relatives, thus determining specific genetic defects that are responsible for underlying disorders.
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