Your English writing platform
Discover LudwigSuggestions(1)
Exact(6)
Gaeta and Pires [ 14] concluded that these genomic changes occur in both natural and resynthesized polyploids [ 14].
In addition, mitigating factors such as co-morbidities and non-mutation-based genomic changes occur over time and may create additional considerations when developing an intervention.
Here I focus on the potential of computational methods to study how genomic changes occur over time and their impact on phenotype or genetic fitness [ 4- 6].
In this article, we consider metagenomics in the domain of microevolution, where genomic changes occur on the same timescale as environmental mixing, as in microbiomes, epidemics, or cancer cell lines.
Remarkably stage 4+ disease appears to have very few genomic alterations when compared with Stage 1 and 4- implying that MYCN amplification is sufficient to drive these tumors to an aggressive phenotype, and although other genomic changes occur, including loss of 1p36 as shown by us and others [ 40], it does not require extensive changes.
Castro and colleagues demonstrated that the stroma of DCIS lesions already possess alterations found in full invasive tumors [ 39], and Ma and colleagues and Allinen and colleagues demonstrated that genomic changes occur in many cell populations of the microenvironment [ 10, 11].
Similar(54)
Many genomic changes occurring late in tumor progression may not be relevant from an etiologic perspective.
Further knowledge about imprinting mechanism in this locus will be required to find what kind of genomic changes occurred with the acquisition of differential methylation.
Few studies have attempted to characterise genomic changes occurring in hereditary epithelial ovarian carcinomas (EOCs) and inconsistent results have been obtained.
These results further support the idea of polyploidy as a dynamic evolutionary process (reviewed in 117), with abundant and rapid genomic changes occurring within a short time period following polyploidization.
Dissecting the genomic changes occurring during domestication and variety diversification has thus a fundamental importance for our understanding of evolutionary processes, in addition to applied interests for improving the desired traits in domesticated organisms and managing the germplasm diversity.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com