The addition of this genome to the two previously sequenced Blochmannia genomes lets us investigate genomic changes in a phylogenetic context.
Our group [ 6, 7] and others [ 8] have demonstrated 'clonal' genomic changes in the genomes of brain and lung tumors by RAPD analysis.
Other genome-wide screens focused on genomic changes in parasites resistant to common malaria drugs.
To increase our understanding of genomic changes in the lineage, the genomes of 58 contemporary cyanobacteria were analysed for shared and unique orthologs.
Lee, B. et al. Clinical Relevance of Genomic Changes in Recurrent Pediatric Solid Tumors.
Brekke HR, Ribeiro FR, Kolberg M, et al. Genomic changes in chromosomes 10, 16, and X in malignant peripheral nerve sheath tumors identify a high-risk patient group.
We used whole-genome sequencing to identify the basis of adaptation in eight replicate evolved strains, and examined genomic changes in light of other growth and physiological data.
In the nearer term, the study identified genomic changes in pancreatic cancer cells that should be sensitive to current or in-the-pipeline treatments.
The challenge is to sort out genomic changes in a possibly large number of strains of the same species, which may vary from one ice sample to another.
To investigate genomic changes in a family with deletion of X chromosome q22.3-q25 associated with normal constitutional and reproductive phenotypes.
Our researchers are devising new approaches to study genomic changes in chordoma, to understand chordoma origins and progression, and to determine which altered genes might be developed into drug targets (Learn more at our Center for Genomics and Personalized Medicine).
