Sentence examples for genomic changes from from inspiring English sources

Based on this phylogeny, we identify pathotype-specific genomic changes from the level of single base changes to the level of multi-gene islands and regions of recombination.

The genomic changes vary from large chromosomal gain or loss to single nucleotide variations or mutations.

Cell lines extensively cultured in different laboratories may have evolved independently and ultimately acquired mutations or genomic changes absent from the original line [ 29].

To our knowledge, this is the first study to use a toxicogenomic approach to compare the genomic changes resulting from primary and PCA air pollutant mixture exposures.

In addition, genomic changes can result from the tissue culture procedures that are required to transform several plant species, leading to epigenetic and heritable (somaclonal) variation of nucleic DNA [8] [10].

The ultimate proof that miRNAs influence the pathogenicity of genomic changes will come from an empirical confirmation of their copy number and expression change, and influence on the expression of their targets.

However, analyses of genomic changes in tumors from the WAP-T121, p53+/- show loss of wildtype p53 allele at chromosome 11 but with minimal increases in other DNA aberrations.

In the AFLP analysis, both loss of the rice parental bands and gain of novel bands were detected in Tong211-LP and its S1 progenies relative to their rice parent Tong211, with variation frequencies of both types of genomic changes together ranged from 2.66%to8.16%6%.

This approach can determine whether apparent expression differences observed at the transcriptional level result from genomic changes such as gene loss or from true differences in expression.

The researchers bolstered the case that cholera was the driving force behind the genomic changes by contrasting DNA from Bangladeshi cholera patients with DNA from other residents of the country who remained healthy despite living in the same house as someone who fell ill with the disease.

Our studies have examined hyperplasia, DCIS and IBC from cross-sectional samples, by both targeted sequencing [ 12] and whole genome sequencing [ 10], to identify genomic changes that occur in progression from these pathologically defined neoplasias.