Sentence examples for genomic burden from inspiring English sources

Besides, the genes involved in motility and chemotaxis impose an additional genomic burden.

Two outlier cases with increased genomic burden of CNVs (RM-M45 and RM-F4) were excluded from the analysis to avoid biased results.

When comparing individually CHD1 deletions, MAP3K7 deletions, and SPOP mutations, we did not observe significant differences in genomic burden for any one lesion.

Some eukaryotes are highly polyploid; for example Paramecium, which can have 800-1000 cofies of the macronucleus, a serious genomic burden.

A subset of patients may thus exhibit increased risk of RM disease attributable to excessive genomic burden of CNVs; however, the finding remains to be confirmed by future studies.

DOI: http://dx.doi.org/10.7554/eLife.09207.006 10.7554/eLiFigure07.007 Figure 1 figure supplement 4. Genomic burden of three subset of prostate cancers defined by the aberration state of SPOP, CHD1, and MAP3K7.

For each individual, we also defined several measures of autosomal genomic CNV burden and compared mean values between phenotypic groups.

We are keenly aware that, especially in fast-growing organisms, a large proportion of realized cost might be incurred by a relatively small number of highly expressed genes so that taking average cost across all sites (or even genes) might not adequately reflect genomic fitness burden.

To reduce the burden in genomic data acquisition for all possible combinations, the corresponding genomic data for drug combination has been predicted by computational methods based on the data of individual ones.

Cancer risk results from a complex interaction of environmental exposures with inherited gene polymorphisms, genetic burden collected during development and non genomic capacity of response to environmental insults.

The majority of TNBCs and HGSCs exhibit a high burden of genomic aberration.