Sentence examples for genomic backbone of from inspiring English sources

The comparison revealed that the genomic backbone of S. Virchow is similar to the genomes of other Salmonella serovars, including key virulence factors.

Enteroaggregative Haemorrhagic E. coli (EAHEC) is a new pathogenic group of E. coli characterized by the presence of a vtx2-phage integrated in the genomic backbone of Enteroaggregative E. coli (EAggEC).

The same DNA metabolism genes had previously been identified in phages FelixO1 and ΦEa21-4 [ 40, 41], suggesting that these genes are part of the genomic backbone of this phage genus.

Besides, analysis by a custom array CGH, targeted to more than 400 candidate genes and a genomic backbone of 370 Kb resolution, did not yield any pathogenic copy number variant (GSM1527009).

Another vaccine (Suvaxyn PCV2 One Dose, Pfizer Animal Health/Fort Dodge Animal Health) is based on a chimeric PCV1-2 virus containing the genomic backbone of the non-pathogenic PCV1, with the ORF2 capsid gene replaced by that of PCV2 [ 4].

Isolates with PFGE type JEGX01.0968 or JEGX01.0843 have the same SNP profile as 2 PFGE type JEGX01.0009 isolates (12_18775 and 12_19824), which suggests that the difference in 3 PFGE types is not associated with differences in the genomic backbone of these isolates.

The analysis of the whole genome sequence of the EAHEC O104:H4 that caused the German outbreak in 2011 showed that the vtx2-phage is inserted in a bacterial genomic backbone typical of EAggEC [ 14], therefore the EAHEC pathotype seems to have arisen from the acquisition of vtx2-phages by classical EAggEC strains.

That is, whereas MLST is an approximation of the mutation rate of the genomic backbone based on sequence analysis of a relatively small number of housekeeping genes, analysis of whole genome differences is a measure of both the rate of mutation and horizontal gene transfer that exists among this species.

All are expressed from their genomic backbone, ensuring physiological processing of the miRNAs.

In conclusion, while short term evolution of L. monocytogenes in natural environments involves limited diversification of the genomic backbone, phage-mediated genetic changes appear to be major mechanisms for diversification and evolution of L. monocytogenes during short evolutionary time frames.

Overall, our data indicate that short term evolution of L. monocytogenes in natural non-controlled environments involves limited diversification of the genomic backbone, but can involve considerable phage-mediated diversification as well as plasmid loss or gain.