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An in-silico subtractive hybridization based-comparative genomic analysis was undertaken using the genome-wide sequence data of these two Psg strains, which allowed us to comprehensively identify the genetic variation between them.
Genomic analysis was done on UCSC genome browser web site [ 41].
Large-scale genomic analysis was conducted with these 7 Nm genomes, 27 additional Nm genomes from GenBank, and 4 other Neisseria genomes.
Comparative genomic analysis was done using Pathan (PTN) genome and the other previously published Pakistani (PK1) genome.
Based on the 13 corresponding serotype strains, including 9 previously completed genomes of this bacterium, a full comparative genomic analysis was performed.
The genomic analysis was also extended to compare the genomes of the other sequenced fungi with varying pathogenic lifestyles to demonstrate whether allergen orthologues are truly ubiquitous in the kingdom or whether they are restricted to the species or genera that are known to produce allergens.
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Interestingly, 115 AIEC LF82 CDSs (2.6%), not found in any E. coli genomes used in our comparative genomic analysis, were identified as LF82 unique CDSs (Table S4).
In the absence of whole genome sequences for most aquaculture species, comparative genomic analysis is useful.
Functional genomic analysis is a challenging step in the so-called post-genomic field.
Such genomic analysis is part of an integrated platform able to evaluate different levels of metabolic pathways of drugs in CM and their influence in the chronicization process.
In this study, primary dermal fibroblast cultures of cows and microarray-based genomic analysis were used to investigate the cause(s) for the variable response to LPS.
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