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The availability of whole-genome sequences has enabled comparative genomic analysis to identify single nucleotide polymorphisms (SNPs).
pneumoniae strains constructed by the accessory genome assembly method described above was used for comparative genomic analysis to identify genetic features distinct to the two outbreak lineages (present in either outbreak lineage but absent in almost all remaining strains).
Their common genetic origin serves a firm premise for downstream comparative genomic analysis to compare parental strains and their offsprings.
EvoFold is a program that uses comparative genomic analysis to identify conserved fRNAs based upon compensatory substitutions required to maintain a particular RNA secondary structure [3].
In an in silico comparative genomic analysis to identify prokaryotic nickel and cobalt uptake transporters, a specific group of TonB-dependent receptors was presented based on conserved regulatory motifs and conserved colocalization in nickel or cobalt transport system operons [42].
In contrast, the RNAz program uses comparative genomic analysis to compare independently predicted RNA secondary structures for a multiple species alignment based upon thermodynamic predictions form each species' primary sequence [12].
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Further sequencing of bacterial genomes of the Thermus-Deinococcus clade should allow more definitive comparative-genomic analysis to elucidate the nature of the common ancestor of these bacteria.
In this study, we propose the use of systematic, comparative functional pan-genomic analysis to build connections between genomic dynamics and phenotypic evolution in polycyclic aromatic hydrocarbon (PAH) metabolism in the genus Mycobacterium.
But Celera's business plan is to sell genome data and genomic analysis tools to the community of university scientists from which the consortium is drawn.
It would be informative to conduct functional genomic analysis similar to that described in this paper on recently discovered coding fRNA predictions in higher eukaryotes to determine the role of fRNAs on coding sequence evolution.
They developed single-cell genomic analysis approaches to characterize and compare DTCs to primary tumors in humans and in animal models of cancer.
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