Sentence examples for genomic Risk from inspiring English sources
Among the T1D genomic risk loci identified by genome-wide association studies, at least six harbour candidate genes that have been implicated directly in B cell differentiation and function (PTPN22, BACH2, PTPN2, IL2 IL21, IL10 and SH2B3; http://www.T1DBase.org).org
Genome-wide association studies (GWAS) revealed genomic risk loci that potentially have an impact on disease and phenotypic traits.
Further, people who obtain a genomic risk profile are likely to focus with horror on the disease for which they are told they are at highest risk.
The genomic risk of gene therapy can thus be prevented by the collective targeting of all contributing factors.
Genomic risk scores were calculated for all 34 SNPs as well as a subset of 7 SNPs that were nearing individual significance.
As costs decline, genomic profiles become common, and popular understanding of risk and its communication improves, genomic risk will become increasingly useful for the individual and the clinician.
Among men with clinically low-risk prostate cancer, we have previously documented heterogeneity in terms of clinical characteristics and genomic risk scores.
A genomic risk score (GRS) was determined for each of the individuals included in this study using the --score command in PLINK V1.07 [19] and the average score calculated.
Analysis and comparison of genomic risk scores for case/control status was performed with logistic regression analysis and Nagelkerke's pseudo R 2. Receiver operating characteristic (ROC) - area under the curve (AUC) was also calculated to investigate the classification (diagnostic) value.
Early indications are that optimal application of genomic risk scores will differ substantially for each disease depending on underlying genetic architecture as well as current clinical and public health practice.
