Sentence examples for genome targets from inspiring English sources

spike-in nucleic acids for both DNA and RNA genome targets (spike-ins were predominately used for unknown samples and not for validation).

Bulk design of primer sets to SNPs or other genome targets can be performed using the Primer3 executable [ 10].

DOI: http://dx.doi.org/10.7554/eLife.03031.006 To understand the relationships between auxin, BR, and phytochrome pathways in regulating genome expression, we compared the ARF6 targets with the genome targets of BZR1 and PIF4.

With respect to the MG1655 and Sakai genomes, out of 5,978 probes, 12 had no target (EDL933 specific), 731 showed nonspecific hybridization or had multiple targets, and 5,235 matched single genome targets.

Herceptin, Gleevec (Glivec, STI-571) and Iressa (ZD1839) represent worked examples of drugs aimed at cancer genome targets (ErbB2, Bcr-Abl and the epidermal growth factor receptor, respectively) that demonstrate promising activity in cancer patients [ 8].

In this review, we try to define the area of synthetic epigenetics and outline the available genome targeting technologies, which are used for targeted editing of epigenetic signals.

We also verified that our CRISPR-Cas9/sgRNA system did not result in non-specific genome targeting by sequencing 9 of the targeted strains (Supplementary file 1B).

Peer-reviewed literature reported that Bxb1 is capable of genome targeting in insect cells [ 13] and targeted integration into the genome of tobacco [ 7].

"This or analogous approaches may one day enable human genome targeting or editing during very early development," notes the paper published in the journal Scientific Reports.

CRISPR/Cas9 genome targeting systems have been applied to a variety of species.

However, Cas9 orthologues and engineered Cas9 variants offer expanded genome targeting capabilities, improved specificity and biochemical properties.