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The resulting gene expression data from 3 WT pre-B cell lines exposed to 0 and 1 Gy IR were processed and analyzed using Partek Genome Suites (Partek® Genome Suites software, version 6.6beta Copyright © 2009 Partek Inc., St . Louis MO, USA) utilizing RMA background correction with quantile normalization and eliminating probe sets with an expression level below 100 in all samples.
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After correcting background noise by subtracting median background signals, data were normalized using Loess method in Partek Genome Suite version 6.5.
We analysed the miRNA profile using the Partek Genome Suite (PGS) software.
CEL files were preprocessed using the Robust Multiarray Analysis (RMA) algorithm with GC-correction on the commercial software Partek Genome Suite (Version 6.4, St Louis, MO, USA).
These 3918 genes were assigned to biologically meaningful gene ontology (GO) categories using GO enrichment analysis (Partek® Genome Suite software, version 6.3).
A selection of genes generated from ANOVA analysis was assigned to biologically meaningful gene ontology (GO) categories using GO enrichment analysis (Partek® Genome Suite software, version 6.3).
The raw data from microarrays were analyzed using Partek® Genome Suite software, version 6.3 Copyright© 2008 (Partek Inc., St . Louis MO, USA).
In order to decipher the underlying regulatory microRNA (miRNA)s in IGF-1/LIF-treated ESSC-derived neurogenesis, we performed in-depth miRNA profiling at 12 days in vitro and analyzed the candidates using the Partek Genome Suite software.
Partek® Genome Suite was used as the first step for quality control (QC) of the data on all the samples with two methods, Pearson correlation and Principal Component Analysis (PCA).
The detection and determination of genomics events (gains, losses, amplifications and breakpoints) was performed using GLAD (Gain and Loss Analysis of DNA) software [ 16] for GeneChip® Human Mapping 50 K Xba Array, and Genomic Segmentation algorithm of Partek Genomic Suite for Genome-Wide Human SNP Array 6.0.
She recently helped develop powerful software--The Genome Parsing Suite--in pursuit of that goal.
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