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Comparative genomic features comprise conservation scores calculated from multi-species genome sequence alignment.
Whole genome sequence alignment analysis by using the MUMmer program revealed that extensive genomic rearrangements have taken place between ATCC 33277 and W83 (Fig. 4).
Beginning with dynamic programming for protein and genome sequence alignment, many algorithms have been proposed.
M.D.W. participated in the shotgun sequence and the genome sequence alignment.
A post-probable phylogenetic tree was constructed from genome sequence alignment with BEAST (Drummond and Rambaut 2007).
The genome sequence alignment was used to generate a table of SNPs from the S. agalactiae core genome.
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In order to visualize conserved genomic regions or chromosomal rearrangements, whole genome sequence alignments were performed by progressiveMAUVE [ 24].
The genome sequence alignments were then performed using the VISTA suite of computational genomics web tools [ 63] (accessible at http://genome.lbl.gov/vista/ ), using the mVISTA option as appropriate for aligning and comparing genomic sequences from multiple species.
Predicted model of the ICAM2 gene structure and ICAM2 genome sequence alignments.
Six genome sequence alignments were performed using Mauve v.2.0.0 [189].
Position-specific conservation scores were derived from multiple whole genome sequence alignments between the human and 16 other vertebrate genomes [25], [32].
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