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The bootstrapped data share the similar characteristics in terms of distribution of fixed points overall (fig. 10; for the whole genome perspectives, see also supplementary figs. S1 and S2, Supplementary Material online).
Ghiselli F, Milani L, Guerra D, Chang PL, Breton S, Nuzhdin SV, et al.: Structure, transcription, and variability of metazoan mitochondrial genome: perspectives from an unusual mitochondrial inheritance system.
Similar(58)
Additionally and/or alternatively, from a genome perspective, plasmids can provide a basis for genomic rearrangements via homologous recombination and so they can facilitate the loss or acquisition of genes during these events, which eventually may lead to horizontal gene transfer (HGT).
Understanding human preimplantation development from a global genome perspective is crucial for basic embryology research, regenerative medicine because of the derivation of human embryonic stem cells (hESC) from single blastomeres [61], [62], and for translational applications in reproductive medicine such as preimplantation genetic diagnosis (PGD) [1], [63], [64].
From the whole genome perspective, the differentially expressed genes (DEGs) in MT and WT were identified using the RNA-seq technology.
In this work, we have presented a whole genome analysis of multiple phototrophic cyanobacteria, with the aim to gain insight into the diversity of cyanobacterial metabolism from a genome perspective.
We also describe several examples that demonstrate the importance of the amphibian genome perspective for reconstructing gene orders of the ancestral tetrapod and amniote genomes, and for understanding the importance of gene order rearrangement in vertebrate evolution.
In the present study we have used long oligonucleotide microarrays and DGE global cross-validation to present a whole genome perspective of EGF-induced gene transcription and its integration into functional cellular networks.
The 3D chromatin structure of most normal cells is such that the chromatin fibers positioned towards the nuclear interior are characterized as: 1) gene-rich (from a 1D genome perspective), 2) actively transcribed (from a nuclear function perspective), and 3) more open/decondensed (from a physics perspective) [ 34- 39].
Moreover, the whole-genome perspective is expected to provide an instrumental contribution to vaccine development, particularly to target those pathogens for which the traditional approaches have failed so far.
Since drought-tolerance is a highly complex trait, a whole-genome perspective is required.
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