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In view of the pivotal importance of our understanding of the way in which genomes navigate their own vastness, this article tries to expand further on the concept of a genome navigation system which is based on pure GA-sequences in order to advance it to a more testable state.
The above outline of genome navigation offers several reasons to explain this finding.
Therefore, genome navigation is a necessary, albeit still little understood, early step of gene regulation.
However, as argued below, genome navigation may also benefit from these insertions.
The article hypothesizes that genome navigation uses these properties of GA-sequences in the following way.
Equally important seems to be the necessity to understand possible failures of genome navigation.
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Regarding the tool in web mode, no other web tool offers the user the possibility to consult executions previously carried out and the integration/visualization of results using a dynamic and friendly environment for navigation genome with jBrowse.
The browser provides easy navigation of genome annotations on the web and has good track selection, zooming, panning, and navigation features [ 19].
The main interface is presented as a typical genome browse, with heading navigation bar, control panel (at the left) and the main browsing canvas.
In this work, we present MetaRoute, a web-based application for efficient (and thus interactive) search and navigation through genome-scale metabolic networks combined with an easy-to-use visualization of the search results.
To allow a comparative navigation through the genome of the hybrid strain with the genomes of Z. rouxii CBS732, S. cerevisiae S288c and Z. bailii CLIB213T, a GBrowse_syn instance is accessible under http://mips.helmholtz-muenchen.de/gbrowse2/cgi-bin/gbrowse_syn/zbailii.
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