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Wu, Y. et al. Reciprocal regulation between the circadian clock and hypoxia signaling at the genome level in mammals.
Large-scale systematic models are now available at a genome level for many biological processes.
Current technologies already allow us high-throughput profiling of epigenetic patterns at genome level.
"Basically you take existing genes and processes and modify them, and that's why humans and chimps can be 99percentt similar at the genome level".
Efficient functional characterization of these genes requires strategies for scaling genetic analyses to the whole genome level.
In the across-family analysis, we detected 8 suggestive QTL and 3 QTL significant at the genome level.
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Genomic comparisons were performed using BLASTN, BLASTX and Mummer at the whole-genome level.
Instead of resolving complex repeat structures on the whole-genome level, we reconstructed the sequences of 100 150 kb BACs.
The international group is already sequencing more birds at the whole-genome level.
With the development of microarray technology, transcriptional changes can be examined at the whole-genome level.
At last, the whole genome features were derived from whole-genome level data.
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