Exact(22)
De novo assemblies created to facilitate core genome identification exemplified the unique genomic characteristics of each bacterial genus (Table 2, see Additional file 7: Table S3 for full results), which were similarly reflected in features of the core genomes including the discovery rate and final number and size of the core genome (Table 3, Fig. 2).
Other than the P. aeruginosa-specific RGP method, we tried to choose functional web-based applications representative of both comparative genomic and sequence-based approaches to accessory genome identification.
The release of the entire genome sequence of T. salsuginea[ 20, 21] has greatly stimulated functional and comparative genomics studies of this species, and has enabled us to perform whole genome identification of T. salsuginea miRNAs, to predict their target genes, and to investigate how the salt-stress response differs from that in Arabidopsis at the level of miRNA regulation.
Comparisons of the architecture of the genome, identification of mutated or modified sequences, and pre-and post- transcriptional regulation of gene expression as disease specific biomarkers are revolutionizing our understanding of the causes of disease and are guiding the development of new therapies.
This approach allows for either specific array probe extension and labeling for genome identification or on-chip isothermal, strand-displacement amplification.
Without a complete genome, identification of the specific methylase for DNA modification to resist restriction enzymes in the host cells is typically a tedious and cumbersome trial-and-error exercise.
Similar(37)
Our whole-genome identification and functional analysis of lncRNAs highlights the important roles of lncRNAs based molecular mechanisms for cellular responses to ENMs in organisms.
We optimized this Sequence Tag Analysis of Methylation Patterns (STAMP) assay for robust, whole-genome identification of methylated DNA segments.
The emergence of high-throughput cDNA sequencing (i.e. RNA/NSR-seq) has enabled whole-genome identification of ASE and has been applied to mapping imprinted loci [ 7, 8].
Whole-genome identification of single nucleotide polymorphisms (SNPs), followed by phylogenetic reconstruction by using maximum parsimony in PAUP 4.0b10 (9 ), showed that all ST562 isolates were closely related; only 26 SNPs were observed among all 17 genomes.
Moving from a whole-genome identification approach to a gene-specific validation phase, we analyzed 14 genes, showing an association to cancer or high differences between twin pairs, in more detail.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com