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Focus chip genes are very suitable for our analysis since they are highly annotated, have low redundancy and their putative promoters are assigned (We identified promoters for 8,110 genes out of the 8,500 of the Human genome Focus chip).
Two different array Affymetrix designs were used: the U133+2 and the human genome focus (HGF) arrays containing 8793 genes (including internal controls).
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Here, we describe the technologies used to manipulate the mosquito genome, focusing on the strengths and weaknesses of each.
The scientists investigate the mechanism for how these pieces move around the genome, focusing on specific kinds found in the yeast and human genomes.
The genotyped SNPs were distributed evenly throughout the genome, focusing on suspected cancer susceptibility genes.
Other studies of the mitochondrial genome focused on mtDNA copy number in brain tumors [ 34].
The Whole Genome Focused Array SNP Typing (WG-FAST) pipeline can identify unknown strains with much less read data than is needed for genome assembly.
Initial approaches to characterising variable number tandem repeats (VNTRs) in the human genome focussed on their utility as informative markers for gene mapping.
Recently, the Affymetrix 500K SNP Chip has been applied to further survey the prevalence of copy number changes across the genome, focusing on rare micro-deletions [ 5].
We have reviewed conflicts between different genetic and epigenetic elements within a genome, focusing on prokarytotic DNases that may cause cell death through chromosomal cleavage.
To reduce this 'signal-to-noise' problem, we developed the Whole Genome Focused Array SNP Typing (WG-FAST) method, where only known SNPs with defined allele states are scored.
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