Sentence examples for genome alteration from inspiring English sources

Genomic alterations were evaluated according to the Genome Alteration Print (GAP) methodology [ 20].

Starczynowski et al. have shown that genome alteration involving <3 Mb detectable by comparative genomic hybridization arrays correlated with better OS in patients with lower-risk MDS.

Copy number alteration (CNA), loss-of-heterozygosity (LOH), copy number neutral allelic imbalance (CNN-AI), subclonal CNA and patterns of tumor DNA ploidy were analyzed using bioinformatical methods such as genomic identification of significant targets in cancer (GISTIC) and genome alteration print (GAP).

Polymorphisms distributed among polyphyletic sets of strains was the most common pattern of genome alteration observed, indicating that strain-specific genome variability is significant.

Using genome-wide computational scans, based on mapping "mate-paired" BES from each Oryza species to the Refseq, all putative major sites of genome alteration along the phylogenetic path of Oryza were recovered.

Uncertainty about possible harmful outcomes can be assumed to be much greater when the genome alteration is accidental and harm may go unnoticed for long than when interventions are targeted and have been tested in model systems, and mathematical predictions can be made.

In this study we investigate if successful anti-TNF-α treatment alters the levels of early mitochondrial genome alterations, which can play a crucial role in governing clinical response or resistance.

His laboratory is developing a robotic system called multiplex automated genome engineering (MAGE) that can perform up to 50 different genome alterations at nearly the same time, creating billions of variants in a matter of hours.

Genome alterations in skin cancers would result from chromosomal rearrangements, aneuploidy and/or polysomies.

Cellular mechanisms of recombination can be used by experimenters to create directed genome alterations.

Ligation of two oligonucleotide probes hybridized adjacently to a DNA template has been widely used for detection of genome alterations.