Sentence examples for genome abnormality from inspiring English sources

(10– 12) Among the various methods for analyzing genome abnormality, array-comparative genomic hybridization (CGH) was developed to detect increases in gene copy number in cell lines harboring amplification of oncogenes.

Therefore, the CNV module is able to detect genome abnormality such as aneuploidy.

Now researchers have found that these drugs slow the accumulation of a type of DNA change called somatic genome abnormalities, or S.G.A.'s, that lead to uncontrolled cell growth.

They have provided accurate and rapid identification of genome abnormalities at high resolution.

DSBs occur during the programmed genome rearrangement process and normal cell metabolism, and can cause genome abnormalities, apoptosis and senescence, if not repaired properly [27].

These researchers suggested that miRNA expression profiling in non-tumor liver tissue would reflect the accumulation of genome abnormalities (the "field effect") in the non-cancerous liver cells.

In addition to cancer genome abnormalities, also the formation of an inflammatory milieu plays a pivotal role in tumor development and progression.

Future studies, especially those that address whole genome abnormalities, population genetics and population structure of these ethnic groups, should further clarify the initiation and development of these important disparities.

The appearance of genome abnormalities and loss of viability in cells other than those directly hit with ionizing radiation (IR) is a well-documented process known as the radiation-induced bystander effect [ 51].

Such understanding would enable statistical prediction of clinical manifestations for genome abnormalities, inference of causative genes from complex disease phenotypes, as well as deeper insights into molecular mechanisms of pathophysiology.

In view of the random nature of chromosomal instability resulting from translocations, mitotic breaks and end-to-end fusions of chromosomes during telomeric crisis, most individual cancers are highly variable in terms of the numbers and types of genome abnormalities involved.