Sentence examples for genetics variants from inspiring English sources
A central question for disease studies and crop improvements is how genetics variants drive phenotypes.
Different genotyping strategies, such as multiplexed SNaPshot, TaqMan real-time PCR or sequencing, are complementary for genotyping all types of genetics variants.
Our study demonstrated that genome-wide association studies would be a feasible way for revealing the potential genetics variants affecting T-cell subpopulations.
The RF method used by Jiang et al. [ 34] is to convert epistatic interactions from a large number of all possible combinations of genetics variants into a manageable set of candidates by reducing the search space for epistatic interactions.
We also used JASPAR to assess the effect of population genetics variants (see below) on the prediction score of motifs within ChIP-seq positive and ChIP-seq negative sites throughout the mtDNA (also see next subsection).
GWAS have found that different genetics variants were associated with asthma susceptibility in children of European and African ancestry suggesting different biological mechanisms could be at the basis of asthma susceptibility in these diverse populations [ 54, 55].
In fact, a number of imaging genetics papers have identified genetic variants that appear to affect the brain and behavior; Hall et al. (2006) and McIntosh et al. (2008) reported a variant in the neuregulin 1 gene that was associated with abnormal cortical function, altered white matter integrity, and with psychosis, and there are many other examples of variants with wide-ranging effects.
Joint consideration of these principles compels novel forms of interdisciplinary analyses, most notably studies that (i) analyze tradeoffs at the level of molecular genetics, and (ii) identify genetic variants that are derived in the human lineage or in specific populations, and then compare individuals with derived versus ancestral alleles.
The OMIM database is a highly reliable compilation of genetic variants from medical and genetics publications.
Distinguishing phenotypically influential from nonfunctional genetic variants remains a major challenge in human genetics.
Until recently, research on the genetics of ADHD has focused mainly on common genetic variants in candidate gene studies.
