Sentence examples for genetics strategy from inspiring English sources

It has emerged as a powerful alternative forward genetics strategy to dissect the genetic and biochemical basis of metabolism, providing a useful approach for functional gene identification with more precision, standardization, robustness and sensitivity (Adamski and Suhre, 2013).

To gain insight into the etiology of NAFLD, we have employed a 'systems genetics' strategy to generate a comprehensive view of the genetic architecture of NAFLD in mice (Civelek and Lusis, 2014; Mato et al., 2014).

A reverse genetics strategy is particularly amenable to dissection of desirable phenotypes where genetic redundancy may complicate a forward genetics strategy.

NLP7 was isolated by reverse genetics strategy and the nlp7 mutants exhibit a nitrogen-starved phenotype46.

Here we demonstrate the utility of the TILLING reverse genetics strategy in identifying novel soybean lines containing desirable seed traits.

In such cases a trait-based approach may offer advantages if combined with a forward genetics strategy.

'Forward' and 'reverse' genetics strategies have been applied arguably in a manner only suitable for much simpler diseases.

Here we devise genomics, in situ hybridization, and mouse genetics strategies to uncover diverse allelic effects in the brain that are not caused by imprinting or genetic variation.

As discussed above, different forward genetics strategies such as classical ALE, chemical, and transposon mutagenesis have been applied so far in Z. mobilis for inhibitor tolerance improvement.

These two laboratories have generated large collections of insertion lines (50,000 and 105,000 lines, respectively) that have been extensively shared among international research groups and thus allowed for deciphering the function of many genes by forward and reverse genetics strategies.

Moreover, systems biology approaches, as the reverse genetics strategies, should be continuously carried out and cross-compared to provide a complete understanding of the inhibitor tolerance mechanism of Z. mobilis, and more biological parts related to inhibitor tolerance should be continuously identified and characterized for robust strain development.