Sentence examples for genetically modified lymphocytes from inspiring English sources

Concurrently, the adoptive transfer of genetically modified lymphocytes to treat patients with haematological malignancies has yielded dramatic results, and we anticipate that this approach will rapidly become the standard of care for an increasing number of patients.

Analysis of the clonal dynamics of genetically modified lymphocytes in vivo is of crucial importance to understand the potential genotoxic risk of this therapeutic approach.

Gary Fathman (Stanford University, Palo Alto, CA, USA) covered the use of genetically modified lymphocytes to treat autoimmune diseases – an approach he has named 'adoptive cellular gene therapy' [ 16].

Finally, the recent ability of genetically modifying lymphocytes has opened possibilities for the in vitro creation of specific lymphocytes with appropriate therapeutic properties.

For the sake of simplicity, these genetically modified T lymphocytes were termed to T lymphocytes, and the T lymphocyte without the genetic modification was termed Mock.

The viability of genetically modified T lymphocytes in the PCgel was assessed with the AlamarBlue assay.

But the Johns Hopkins scientists were surprised to find a higher death rate in mice that had been genetically modified to be lymphocyte-deficient, at 40percentt, while the death rate in mice with lymphocytes was just 10percentt.

Recently, two clinical trials have been started with genetically modified, IL-12-secreting lymphocytes.

Clémenceau, B. et al. Antibody-dependent cellular cytotoxicity (ADCC) is mediated by genetically modified antigen-specific human T lymphocytes.

Rather than becoming exhausted upon engagement of PD-L1+ tumors, we hypothesized that CD8+ cytotoxic T lymphocytes (CTL) genetically modified to express this PD1 CD28 chimera would exhibit enhanced functional attributes.

T lymphocytes can be genetically modified to express chimeric antigen receptors (CAR) comprised of antibody-T cell receptor hybrids that redirect them to target and destroy cancer cells.