Sentence examples for genetic stimulation from inspiring English sources

In addition, pharmacological or genetic stimulation of UBIAD1, as a CoQ10 biosynthetic enzyme, represents a promising therapeutic approach for antioxidant-related diseases such as aging and cancer.

Previous slice studies indicating an effect on clearance used genetic or stimulation paradigms that differed from those used here (Amiry-Moghaddam et al. 2003; Strohschein et al. 2011).

Finally, we build on the Research Domain Criteria framework, highlighting the notion that mental illnesses can be conceptualized as dysfunctions of neural circuitry present across conventional diagnostic boundaries, to sketch how network-based methods can be combined with pharmacological, intermediate phenotype, genetic, and magnetic stimulation studies to probe mechanisms of psychopathology.

It is therefore essential to elucidate the molecular basis of their genetic reprogramming upon stimulation of various sorts towards a better understanding of immunity and improvement of DC-based immunotherapies.

Across all three genetic subgroups HRG stimulation increases sensitivity to MM-111, and decreases sensitivity to all four remaining drugs, particularly lapatinib.

These findings clearly demonstrate that arsenic carcinogenesis in the liver involves a complex interplay between multiple genetic events, including stimulation of oncogene expression, liver feminization, cell cycle dysregulation, and disruption of cell cell communication.

Interestingly, mTORC1 activity is not an absolute requirement for healthy mitochondria, as mitochondrial function can be restored in mice lacking mTOR through the genetic or pharmacological stimulation of mitochondrial biogenesis pathways [ 53].

Based on analysis of a cohort of patients with recent-onset inflammatory arthritis, the provocative suggestion has been advanced that the sole role of the shared epitope is to provide the genetic basis for stimulation of T-cell help in anti-CCP antibody formation and that it does not otherwise contribute to the development of RA [ 8].

This chapter discusses researching efforts in tendon and ligament tissue engineering by examining key approaches with cellular entities, inductive biochemical factors, scaffolds, biomechanical stimulation, and genetic modification.

Population-based studies suggest a role for chronic immune stimulation and genetic factors in the causation of lymphoplasmacytic lymphoma (LPL /Waldenström's macroglobulinemia (WM).

Conversely, insulin stimulation or genetic ablation of the voltage-dependent anion channel do not affect cell death induction by the hexokinase II peptide.