Exact(1)
Regardless of some genetic specifications, the following particularities concerning each of the syndromes discussed above are consensual nowadays: HBOC syndrome is mainly associated with ovarian HGSC, which seem to arise in the fallopian fimbriae and have better prognosis than sporadic cancers.
Similar(59)
Even among the yeasts, modes of centromere inheritance vary, from complete genetic specification, as in Saccharomyces cerevisiae, to genetic specification without clear sequence specificity, as in Schizosaccharomyces pombe (Polizzi and Clarke 1991), to complete epigenetic inheritance, as in Candida albicans (Ketel et al. 2009).
We provide evidence that this shape change relies on extrinsic signals subsequent to genetic specification.
The genetic specification of the compartmentalized pancreatic acinar/centroacinar unit is poorly understood.
This is an interesting results at it seems to imply that no costly detailed genetic specification of inter-LN connectivity is necessary to achieve a functional MGC.
In this paper, we explore the possibility of genetic specification of the patch system.
These findings suggest that NRP1 is dispensable for the genetic specification of tip cells.
NRP1 is therefore not required for the genetic specification of tip cells.
Differentiation of neuronal subtypes, after genetic specification, is subject to multiple signals many of which generate and modify electrical activity of the cognate neurons (Borodinsky et al., 2014).
SATB1 therefore forms the link between a developmentally imposed genetic specification program and extrinsic environmental cues; a prime example of nature and nurture intertwined to specify cell fate.
These results strongly suggest that Otp and Sim1 genes in the alar plate Pa domain (specifically, at the ventral subdomain of Puelles et al. 2012) may also be involved in the genetic specification of the alar GHRH cells.
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