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The paper, "Social Disadvantage, Genetic Sensitivity and Children's Telomere Length," was published online April 7 in the Proceedings of the National Academy of Sciences.
Kate's blood reveals a genetic sensitivity to carbohydrates, explaining in part why she doesn't respond well to low-fat diets, which tend to be abundant in such refined carbs as pasta and rice.
Genetic sensitivity to the bitter taste of 6-n-propylthiouracil (PROP) has been reported to determine preferences for bitter, sweet, and fat-containing foods, affect dietary habits, influence body weight, and modify chronic disease risk.
Genetic sensitivity to the environment: The case of the serotonin transporter gene (5-HTT) and its implications for studying complex diseases and traits.
The mushroom is not bitter for those who lack genetic sensitivity to bitter taste, a trait endowed by the gene TAS2R38 (taste receptor 2 member 38).
Furthermore, studies in rodents indicate a shared genetic sensitivity to ethanol, anxiety, and stress/HPA axis response [15], [16], [17].
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The researchers also report that boys with genetic sensitivities to their environment have shorter telomeres after experiencing stressful social environments than the telomeres of boys without the genetic sensitivities.
A broad definition of environmental health encompasses not only the adverse effects associated with exposure to chemicals in air, food, and water, but also the interaction of these exposures with genetic sensitivities and nutrition.
Tepper, B. J. & Ullrich, N. V. Influence of genetic taste sensitivity to 6-n-propylthiouracil (PROP), dietary restraint and disinhibition on body mass index in middle-aged women.
Physiological similarity to mammals, ease of genetic manipulations, sensitivity to pharmacological and genetic factors, robust behavior, low cost, and potential for high-throughput screening contribute to the growing utility of zebrafish models in this field.
Here we show that in the absence of Htz1 the SWR1 complex causes genetic instability, sensitivity to stress conditions and genome-wide transcriptional misregulation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com