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Our study not only validates the genetic schemes for the isolation of RNA polymerase mutants that alter fidelity, but also sheds light on the mechanism of transcription accuracy.
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In addition to novel markers for the identification of balanced progeny, others have created transgenic insertions on balancer chromosomes for the convenient delivery of key enzymes into genetic schemes; these include transposases for P (Lindsley and Zimm 1992) and Minos (Metaxakis et al. 2005) transposon systems, and Cre (Siegal and Hartl 1996) and FLP (Chou and Perrimon 1992) recombinases.
Constructing transgene arrays in this fashion would mitigate the need for a large number of landing sites, while simultaneously simplifying complex genetic schemes.
The genetic cross schemes for the microarray are outlined in Table S2.
One example for such an aid is the genotype builder introduced here as a quick and easy way to generate images of flies to illustrate genetic mating schemes for training or publication purposes.
A novel genetic scheme is then proposed for attaining a near global optimal performance.
Recombinant F2 progeny were scored for presence of the mapping dominant markers and for absence of the balancer dominant marker (see genetic scheme in Figure 1A).
In this paper we propose a generic scheme for the validation and verification of molecular genetic tests for diagnostic use.
On the wilder fringes of the genetic engineering community, there are true believers prattling of the gene-rich and the gene-poor - Huxley's alphas and epsilons - and busily engaging in schemes for genetic enhancement and - to go one better than Brave New World - for immortality.
Moav R.A. and G.Wohlfarth, 1967 Breeding schemes for genetic improvement of edible fish.
Various schemes for genetic screening based on risk factors for mutations have been proposed, which include screening for RET, SDHB, SDHD and VHL in case of abdominal paragangliomas [ 2, 3].
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