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Early-onset bipolar disorder can be made worse by careless administration of the wrong class of psychiatric drugs to children at risk for this highly genetic, potentially lethal illness (front page, March 20).
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Other heavily exploited fish populations have suffered from reduced genetic diversity, potentially reducing their adaptive potential (Hauser et al. 2002; Hutchinson et al. 2003).
However, each study showed variability within the limited genetically-defined groups, consistent with additional genetic variations potentially represented by the extended haplotypes, contributing to phenotypic noise.
The future of genetic studies potentially may help people understand their personal risks and potential treatments for disease.
Schizophrenia is a heritable mental disorder with a complex genetic aetiology potentially implicating glutamatergic dysfunction.
Moreover, spontaneous mutations can occur on any number of genetic backgrounds, potentially revealing critical genes that require a specific genetic context.
PD in humans is therefore thought to be a function of genetic predisposition, potentially associated with how efficiently an individual is able to metabolize dopamine-related neurotoxins.
While this is not in itself an evolutionary response, as environmental conditions continue to worsen, heterozygote advantage could help maintain genetic variation, potentially buying time to allow the species to respond via adaptation.
Our DNA is under constant attack from many sources: Radiation, ultraviolet light, and contaminants in our food and in our environment can all wreak havoc on our genetic material, potentially leading to cancer and other diseases.
The motivation for introducing the new blood test is safety, but controversy has been building based on concerns that far more parents would be inclined to find out if their baby was affected by a genetic disorder, potentially leading to more pregnancies being terminated.
This data helps to refine mutation risk estimates among women with TNBC, allowing for more personalized genetic counseling potentially aiding in improved patient decision-making.
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