Sentence examples for genetic normalization from inspiring English sources

Our results showing that nuclear levels of Cyclin D1 are reduced in the dorsal telencephalon of Ts65Dn embryos and that genetic normalization of Dyrk1a dosage restores Cyclin D1 to normal levels in the trisomic embryos suggests that the action of DYRK1A on Cyclin D1 turnover contributes to the altered cell cycle parameters observed previously in the VZ of these embryos (Chakrabarti et al., 2007).

Thus, the fact that genetic normalization of Dyrk1a dosage in trisomic Ts65Dn embryos is sufficient to normalize the production of early-born cortical neurons in these embryos shows that Dyrk1a is the only gene in the triplicated region responsible for the phenotype.

Accordingly, the genetic normalization of Dyrk1a dosage in Ts65Dn progenitors increased the amount of total and nuclear Cyclin D1 to euploid levels (Fig. 7B).

The mean intensity of the background staining observed in dfmr1 null flies was subtracted from the mean fluorescent intensity measured in each ROI of each genetic background before normalization to WT to calculate the fold change.

Furthermore, since the measure of Smouse and Peakall [ 23] depends on number of alleles (and loci), it puts strong limitations on comparisons between populations and genetic markers without appropriate normalization.

As mentioned before, there are no NLP tools available for genetic testing information extraction and normalization.

Integrating variants from heterogeneous sources requires left-aligned normalization on all genetic variants, which in our case was performed using an algorithm proposed by Tan et al.

— Andy Revkin (@Revkin) 28 Jul 13 Normalization of the role of genetic modification in agriculture — and a fadeout for "frankenfood" campaigns — is most likely to come as consumers realize the varied applications of this versatile, and increasingly vital, technology.

SK carried out molecular genetic measurements and data analyses, developed the normalization concept and drafted the manuscript.

Among the information is the number of replicates, age of plants, genetic background, growing conditions, method of microarray data normalization, and the lab responsible.

The second method did not employ normalization, rather each individual's adjacent normal sample was compared to the matching paired tumor tissue, providing a genetic control for individual-to-individual variation in DNA methylation.