Sentence examples for genetic exposure from inspiring English sources
Parental BMI might be an indicator of the family environment, favouring or not obesity development, beyond of a genetic exposure.
In contrast, GE correlation refers to genetic exposure to the environment in that experiences can be correlated with genotype.
ORG with values greater than one suggests that disease is proportional to increased genetic exposure and inversely proportional for values less than one.
SUR is a generalization of OLS linear regression, which allows simultaneous model fitting between two different outcomes (serological levels in 1981 and 1994), and a consistent genetic exposure.
The word interaction is sometimes used to describe the joint effects of a genetic exposure and a second factor that is positioned on the causal pathway between the genetic exposure and a disease phenotype; in epidemiology, this process is termed mediation, which differs in meaning from interaction.
As genetic exposure is constant throughout life, we classified participants as having DM regardless of whether DM was established before or at the baseline examination or during a follow-up period of 14.0±3.8 years after the baseline examination.
Summary scores increase power in modeling genetic exposures [52].
Epistasis, defined as the deviation from additivity of effects observed at multiple genetic exposures [18], [19], may also explain part of the genetic heritability that is left unexplained for most complex disorders [20].
Additional concerns in the use of case-control studies are the potential for selection bias and the possibility of confounding due to unmeasured differences between case and control status that are associated with genetic exposures.
Methods to detect epistasis, or gene-gene interactions, in large search spaces have been under development from several sources since Risch et al. suggested interaction analysis as an important avenue for the discovery of genetic exposures related to complex disease [1].
12 Instead of the single exposure evaluated in a non-genetic case-control study (such as smoking), these studies examine hundreds of thousands of genetic exposures simultaneously.
