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Different genetic end points can be monitored in the same exposed population of bacteria.
Confidence in results from monitoring genetic end points in environmentally or occupationally exposed individuals can be improved with knowledge of the normal variability of changes in genetic end points in the general population.
The effects of genotoxic substances on ecosystems should be assessed using various test systems with multiple genetic end points.
In the medaka test system, four genetic end points are evaluated: dominant lethals, total mutations, viable mutations, and malformations.
The fractions may be tested with a broad range of microbial assays covering numerous genetic end points as well as both with and without mammalian microsomal activation.
When legally required mutagenicity testing of chemicals is undertaken, the important genetic end point of aneuploidy is not included because validated test methods are lacking.
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In hospital pharmacy personnel adopting high standards of safety, Pilger et al. [ 51] observed that frequencies of MN and SCE were similar to those of controls, whereas small increases in these genetic end-points were found in accidental contamination events.
Male Denisovan H.sapiens hybrids, in other words, represented a genetic dead end.
Like a spent royal family dynasty, the wolves of Isle Royale, Michigan, have reached a genetic dead end.
Previous studies of hymenopteran species with sl-CSD mostly recognized diploid male production to be a genetic dead end (see Table 4).
The genetic toxicity end point includes gene mutation and chromosomal aberration/damage (CAD).
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