Our study focused on investigating a genetic association through categorization (sensitive or resistant) while Park et al, correlated sensitivity with protein expression level.
Observations such as these have led Cooper et al. (2003) to conclude that race "has not shown to provide a useful categorization of genetic information about the response to drugs, diagnosis, or causes of disease".
These findings suggest that the genome-wide supported variant of schizophrenia had larger effect on GM volumes of the inferior frontal gyri than diagnostic status, and support that GM volumes abnormalities were prominent intermediate phenotypes bridging the gap between a susceptibility genetic variant and diagnostic categorization.
We demonstrate that Categorizer provides improved categorization and enrichment results of genetic modifiers of Huntington's disease compared to a classical GO Slim-based approach or categorizations using other semantic similarity measures.
This report describes how recognition of biologic and genetic factors has permitted risk categorization and resulted in new treatment protocols that individualize care.
One strategy for gene discovery uses neurobiological quantitative traits (QT) as intermediate phenotypes that reflect the underlying genetic vulnerability better than diagnostic categorization, such as schizophrenia [ 9, 10].
Although the categorization of a genetic group employed in this study differed from that employed previously [ 12], a large number of regionally-differentiated rabies virus variants were identified, and were widely distributed in both previously-studied and new areas of Brazil.
Socially and politically tinged aspects of reductionist research in biology, such as racial categorizations based on genetic profiles, also continue to provoke philosophical analyses (see Section 5).
The results highlight a marked genetic structure associated with the fourth categorization criterion that considers whether populations live within the dry savanna biome or outside of it (Table 3).
This umbrella categorization covers a host of genetic and medical phenomena (from micropenises to undescended testes that turn out to be ovaries to partially fused labias).
Current criteria to distinguish individual NHL subtypes such as morphology, immunophenotype, and genetic abnormalities do not allow reliable subtype categorization and prediction of treatment response for NHL cases.
