Sentence examples for genes which function from inspiring English sources
In the last years, several studies used synthetic genetic interaction data, determined either through synthetic genetic arrays (SGAs) [ 12, 13] or epistatic miniarray profiles (EMAPs) [ 14, 15], to deduce functional relationships between gene pairs, identify sets of genes which function within the same complex or pathway and to predict the function of uncharacterized genes.
Examples involving networks include the transcriptional regulation circuits formed by Hox genes and the Drosophila segmentation genes, which function in both early and later developmental events.
Its activation leads to transcriptional induction of ATF6-regulated genes which function primarily to restore correct protein folding in the ER.
BAZ2A is a member of the bromodomain family of genes which function as integral components of chromatin re-modelling complexes [31].
Alternative oxidase (AOX) and catalase genes, which function in alleviation of reactive oxygen species (ROS) generation, were up-regulated in microarray analysis (Table S6).
Some of the best-characterized targets of this transcriptional activation complex belong to the Hes -and Hey family of genes, which function as transcriptional repressors of further downstream targets like Math-1 (mouse homolog of human Hath-1) [23] [25].
Our results suggest that neural crest-derived cartilage evolved by serial cooption of genes which functioned primitively in mesoderm.
Instead, our data suggests piecemeal assembly of the vertebrate cartilage gene network via repeated cooption of genes which functioned primitively in the mesoderm of the pre-vertebrate chordate.
Increases in the expression of pdu genes (which functions in propanediol utilization) and the associated regulator (pocR) were also noted in glycerol-exposed cells.
For example, seed-specific tae-miR1127b which were only present in developing seed (Additional file 5) targeted riboflavin biosynthesis protein Rib gene/amino acid permease gene, which function in seed development [ 45, 46].
We propose that ITF-2 is a TCF-regulated gene, which functions in concert with other TCF target genes to promote growth and/or survival of cancer cells with defects in beta-catenin regulation.
