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These two Mbp clones exemplify a class of genes which display a strong variability in their differential expression across the analyzed samples (Figure 3C).
Interestingly, we found that even a subset of genes which display differential expression upon the treatments was bound by p53 to a comparable degree upon both treatments.
The four isoforms of CaMKII (α, β, γ, and δ) are encoded by different genes, which display distinct but overlapping expression patterns (Tombes et al, 2003).
The serum amyloid A (SAA) family of proteins is encoded by multiple genes, which display allelic variation and a high degree of homology in mammals.
From microarray experiments, genes, which display stable expression across all fold-changes are likely to be good candidates for normalization for qPCR.
Let us proceed with the task of identifying the particular groups of genes, which display significant differences in the intragene methylation profiles between the cell types.
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While the overall genome structure of these phages resembles the well-studied coliphage N4, these Pseudomonas phages encode a cluster of tail genes which displays significant similarity to a Pseudomonas aeruginosa (cryptic) prophage region.
We also included ∼100 genes which displayed the most variation across the 305 experimental conditions as negative signals.
We also included 39 E. coli genes which displayed the most variation across the 305 experiments and not in the RegulonDB target set as negative genes.
Interestingly, GAPDH was detected in the promoters of several genes which displayed an increased expression in the activated T cells, but not in the promoters of genes that were unaffected or down-regulated (Fig. 4).
French et al. [34] studied the genomic determinants of methotrexate polyglutamates (MTXPGs) variation in acute lymphoblastic leukemia (ALL), and found that ME2 is among 7 genes which displayed all 3 types of genomic variation associated with MTXPGs.
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CEO of Professional Science Editing for Scientists @ prosciediting.com