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As expected, deletions of these genes were sensitive to a broad range of DNA damage reagents (Table 1).
Two genes were sensitive to dosage: one encoding glycolytic enzyme aldolase A (Aldoaa) and the other microtubule motor kinesin family member 22 (Kif22).
In females, 474 genes were sensitive to the magnetic field, of which 115 were common to flies in two different experiments.
Strains with deletion mutations in these genes were sensitive to HMF with an extended lag phase, for example, genes OTU1 and SHP1.
Interestingly, these C. albicans genes were sensitive to low glucose concentrations, like their homologues in S. cerevisiae (Yin et al., 2003).
The latter findings are consistent with a previous report whereby growth-related genes were sensitive to high dosage of gene expressions, and stress responsive genes were tolerant to high dosage [ 47].
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As in vertebrates, neural patterning genes are sensitive to Bmp signaling.
These results suggest that PsPINs and PsAUX1 are auxin-inducible genes, and that the expression of PsPINs and PsAUX1 genes is sensitive to gravistimulation.
We found that 27 of the 72 human TRIM genes are sensitive to IFN.
The mRNA expression of these genes is sensitive to increased activity in neurons [28].
This may imply that the regulations of these four genes are sensitive to the changes of the system.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com