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The TF genes were initially synchronized with version 5.0 of the RGAP Pseudomolecule and genome annotations resulting in 2221 unique genes with appropriate annotation in version 5.0.
In this far-reaching review, we examine what is currently known about ALS genetics and how these genes were initially identified.
Five to ten genes were initially selected for each organism of interest.
Most PCP genes were initially identified in Drosophila or Xenopus and their homologues were subsequently found in mammals.
The Reg genes were initially identified in the regenerating pancreas, and are known to accumulate in islets from patients with type 2 diabetes [23], [24].
Genes were initially mapped to the sequenced maize genome using LASTZ, and then visually proofed and corrected using GEvo part of the CoGe comparative genomics platform (http://genomevolution.org/CoGe/) [17].
In an effort to determine whether the tiling array data accurately reflects the gene expression profile, HRG-mediated up- and down-regulated genes were initially identified from the histone acetylation and RNA map data (see Materials and Methods section).
Genes were initially filtered using Illumina detection score.
Two genes were initially selected as good candidates.
Protein coding genes were initially identified by BLASTX [ 44] searches of NCBI protein databases.
Drought-responsive genes were initially identified in Arabidopsis using microarray analysis.
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