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WNT signaling genes were highly expressed in the smooth muscle/myoFBs clusters of cells.
A common feature of both positive and negative networks was that their top 200 coordinate genes were highly interconnected in NCCs (Supplementary Fig. 7b, c).
As sk11 and sk12 single mutants exhibited indistinguishable phenotypes from wild-type plants, we further created sk11 sk12 double mutants since these two genes were highly similar.
Both ORFs and LOC genes were highly significant between 2 to 7-fold difference and AUC value of >0.75 (FDR p-value < 0.01).
Furthermore, SRS5 and BRI1 genes were highly expressed in Srs5 and d61-2 mutants.
Others chemokine genes were highly induced, including CCL20, CXCL2, CXCL3 and CX3CL1.
In contrast, using this approach, aging effects on inflammatory genes were highly significant (p = 0.01).
The remaining JL03 flp operon genes were highly homologous to those from H. ducreyi 35000HP.
Additionally, other lipid metabolism-related genes were highly affected on the 45E% fat diet.
However, changes in inflammation related genes were highly variable.
Additional prophage genes were highly expressed in the individual strains.
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