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The affected genes were furthermore tested for significantly overrepresentation of GO terms among both induced and repressed genes as presented below.
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The number of genes is furthermore limited to include only those that have a fold change ≥ 2 and a p-value ≤ 0.05 (TopHits) in at least one of the contrasts.
The histones on the chromatin of the Cdx-2 gene are furthermore acetylated after the transcriptional start site, indicating that the promoter is transcriptionally active.
Distribution and orientation of gene trap virus insertions were, furthermore, consistent with a high likelihood of inducing loss-of-function mutations.
This approach can be used for the functional inactivation of any mutant keratin allele regardless of the position of the mutation within the gene and is furthermore applicable to the treatment of other inherited skin disorders.
As most of the corresponding m-values were close to the detection limit of the DNA microarray, expression of this gene set was furthermore examined by real-time RT-PCR.
Furthermore, genes were classified into Gene Ontology [64] or PANTHER groups [65] using the DAVID functional annotation analysis tool (http://david.abcc.ncifcrf.gov/).abcc.ncifcrf.gov/
Furthermore, genes were enriched in SBMA motor neurons in several key pathways including p53, DNA repair, WNT and mitochondrial function.
Furthermore, genes were then filtered to include only predicted targets, and targets were validated through in vitro experiments.
Furthermore, 4/13 genes were upregulated at 1.8 Gy 168 h after injection of 211At.
Furthermore, 984 genes were identified in myogenesis.
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