In contrast, these genes were either downregulated or not regulated in the susceptible cultivar (Fig. 4b).
The other candidate genes were either not differentially or extremely low expressed, or encoded for an unknown protein, and therefore, were not pursued further.
The expression analysis revealed that entire clusters of genes were either up- or downregulated upon combination of fibroblasts and keratinocytes in cultured skin grafts.
When Δ133p53 was overexpressed in CRL-2097 fibroblaSupplementaryntary Figure S2a), similar results were obtained: p21WAF1, PAI-1, IGFBP7 and miR-34a were repressed, while the other three genes were either unchanged (PUMA) or modestly downregulated (BAX and p53R2) (Supplementary Figure S2b).
Together, 10,537 genes were either significantly up- or down-regulated during 30 minutes to 12 hours of drought treatment (Additional file 2: Table S2).
On the contrary, the isolate was considered as non-ESBL-producer organism when blaTEM, blaSHV and blaCTX-M genes were either not detected or when amplified blaSHV or blaTEM genes did not carry any ESBL-associated substitution.
These 1124 genes were either directly or indirectly regulated by Mta1.
During differentiation the genes were either down- or upregulated (Figure 5B, groups I and II, respectively).
These genes were either clustered around the targeted allele or over-represented on that chromosome.
Values for other genes were either modestly positive (for sera5, Pf38 and msp7), or negative.
The remaining 30 imprinted genes were either biallelic or below detectable levels in adult peripheral blood leukocytes.
