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If partial genes were counted, 97% to 98% of the core genes were found in the genomes, suggesting that the assemblies captured most of the genes in the target taxa.
Detected endemic genes were counted based on treatment means.
Multiple copy genes such those on IS elements or rRNA genes were counted only once.
Up- or down-regulated genes were counted when representing probes were significantly different between test and control groups at p<0.01.
aDuplicated genes were counted only once.
Overlapping genes were counted separately following this scheme.
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g, True-positive rates (for which a priori known essential genes are counted as positive) when considering the genes that are core fitness genes for at least k cancer types (blue curve) as predictions and the deviance of the number of these genes from expectation (computed using the randomized data shown in f; red curve).
d, True-positive rates (for which a priori known essential genes are counted as positive) when considering the genes that are depleted (fitness genes) in at least m cell lines (blue curve) as predictions and the deviance of the number of these genes from expectations (computed using the randomized data shown in c) for all possible values of m (red curve).
The number of genes was counted within each species first (with function (1)).
The number of differentially expressed genes was counted in each window, and the distribution of differentially expressed genes was compared to a random distribution.
Within each window the number of immune genes was counted to obtain a density distribution of immune genes along the chromosomes (black lines in Fig. 1A).
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