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The majority of cellular response overview genes were attributed to biotic stress (934 genes), abiotic stress function (361), redox (209) and cell division (200) (Fig. 2d).
Remarkably, a total of four genes were attributed roles in chitin metabolism, including chitinases and chitotriosidase.
In the category of organismal systems, all 19 mapped genes were attributed to the plant immune system classification.
Each class was then split randomly into a training set and a test set, 2/3 of genes were attributed to the training sets.
Indeed, in a recent in-silico multiple-knockouts study of the robustness of the yeast's metabolic network [ 7], 74% of the genes were attributed some functional contribution, as opposed to only 13% found to be essential using single knockouts.
Thirty per cent of these genes, all down-regulated, were assigned to the 'Signal transduction' biological process; the only 7 up-regulated genes were attributed to 'Nucleic acid metabolism' (Giyd2 and Hspa1a), 'Cell death' (Lgmn), 'Cell differentiation' (Erdr1 and Vim) and 'Reproduction' (Cited2 and Amh).
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In that group, mutations of three genes are attributed to germination dormancy.
Additionally, a relatively high percentage of the observed variation in the expression of these 20 genes was attributed to the cis-SNPs, approximately 26% (range = 8 58%) in the leukemia cells and, 34% (range = 14 64%) in the normal leukocytes.
The shared variation between genes is attributed to biological causes.
Next, we found what fraction of genes is attributed to the group on the scale of the whole genome.
First, we found what fraction of genes is attributed to the group on the scale of the profile.
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CEO of Professional Science Editing for Scientists @ prosciediting.com