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However, the induction of Hsp genes was normal after a 10 min heat shock treatment (Fig. 6B, lanes 1 4), suggesting that menin was not required for the initiation of the stress response but was critical for sustaining the expression of heat shock protein genes.
Fifty-one signature transcripts were tightly associated with α-synuclein expression, whereas in age-matched tau transgenic Drosophila, the transcription of α-synuclein-associated genes was normal, suggesting highly distinct pathways of neurodegeneration [ 83].
Second, the mutation effect on the PIN2 protein level seems to be due to degradation but not transcription or translation of PIN2, because the transcription of mutant PIN2 genes was normal (Additional file 1: Figure S6B) and the wortmannin-restored protein levels of mutant PIN2 were similar to those of wild-type PIN2.
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Those genes are normal in most human narcoleptics but they still lack hypocretin, according to separate studies by Dr. Mignot's group and a team led by Jerome Siegel, a neuroscientist at the University of California, Los Angeles.
BRAF and EGFR genes were normal in the PIK3Ca mutant lines.
The other genes were normal.
In contrast, tumor suppressor genes are normal genes that must be inactivated or lost for tumor development.
The expression pattern of developmental genes is normal in His C mutant embryos.
9) In addition, can the authors exclude that the expressions of important developmental genes are normal at E6.5?
If sequencing of all three genes is normal for a Mendelian family, then screening for duplication of the APP gene should also be considered [ 65, 117].
Because bacterial species that carry ESBL genes are normal inhabitants of the gastrointestinal tract, food is a potential source of them.
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