Sentence examples for genes to block from inspiring English sources

Injecting genes to block myostatin could help not only those with muscular dystrophy but also anyone suffering the routine loss of musculature that comes with aging.

We hypothesize that testis antler dysgenesis results from exposure of pregnant females to an estrogenic environmental agent(s) acting epigenetically to transform testicular cells and also to alter the primordial antler pedicles and affect expression of the Insl3 or other genes to block transabdominal descent of fetal testes in most animals.

The bioethanol-producing strain, E. aerogenes ATCC 29007, was engineered by deleting the D-lactate dehydrogenase (ldhA) gene to block the production of lactic acid.

"So that was a real shock to the system because we thought it would be a wonderful protein and gene to block," he says.

To this end, we designed a morpholino antisense oligonucleotide (MO) targeting the translation initiation codon and 5'-UT region of the zTERT gene to block translation of zTERT mRNA (zTERT-MO1), and injected this MO into zebrafish embryos at the 1 2-cell stage.

This is because it takes only one gene to block metastasis, whereas it takes the coordinated expression of multiple genes to allow metastasis.

To realize succinate accumulation under aerobic condition, inactivation of sdhA gene to block the conversion of succinate to fumarate in TCA cycle is necessary).

Deleting a gene to block the development of neurons called the Atoh1 neurons in the RTN/pFRG region caused mice to die shortly after birth because they were unable to establish a normal respiratory pattern (Rose et al., 2009).

In the present study, we constructed an RGD-modified, αvβ3 integrin specific adenovirus encoding dnIκB as a therapeutic gene to block NF-κB-dependent signal transduction in endothelial cells.

One mechanism to explain this decreased sensitivity is the up-regulation of miR-125, which binds to the 3′-UTR of the p53 gene to block translation (Le et al. 2009) in cell lines resistant to paclitaxel and doxorubicin (Kovalchuk et al. 2008; Zhao et al. 2008).

The literature of speciation mechanisms has some examples of cleverly designed experiments to isolate genes required to block gene flow among closely related species.