Sentence examples for genes through an from inspiring English sources

Therefore, the increase of the methylation level of GREs in the brain can regulate many genes through an increase in GR binding.

Putzbach, W. et al. Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism.

The core FA-responsive transcriptional network consists of carbon source-sensing transcription factors that regulate key target genes through an overlapping feed-forward network motif (OFFNM).

Exposure to low temperature, dehydration and salinity stresses induces a common subset of genes referred to as cor, cold regulated or rd, responsive to desiccation genes through an ABA-dependent or ABA-independent pathway (Liu et al., 1998; Thomashow, 1999; Shinozaki and Yamaguchi-Shinozaki, 2000; Yamaguchi-Shinozaki and Shinozaki, 2005).

Alterations in SHP and Cyp7a1 by FGF19 and FGF21 were observed even in Fgfr4 KO mice, indicating that with this acute treatment, both endocrine FGFs can modulate expression of these genes through an FGFR4-independent pathway (Fig. 3B).

Transcribed (but untranslated) pseudogenes may also play a role in the regulation of orthologous (translated) genes through an RNA interference mechanism, and so the low dN/dS values may indirectly reflect purifying selection acting on the protein coding region of the regulated orthologous gene [24].

The ability to selectively silence genes through a technique called RNA interference (RNAi) has revolutionized biology.

Development and homeostasis require coordinate regulation of neighbouring genes through a process termed locus control.

Riboswitches are RNA elements that control the expression of genes through a variety of mechanisms in response to the specific binding of small-molecule ligands.

For the human datasets we used the 'regulatory circuits' generated by Marbach et al.41 in which regulators were linked with target genes through a series of steps starting from binding motifs in active enhancers using FANTOM5 project data.

It describes technologies that spread a gene or particular suites of genes through a population.